Stephen M. Roth, Ph.D.

Associate Professor

Exercise Physiology, Aging and Genetics

Publications

Books:
Roth, S.M. (2007). Genetics Primer for Exercise Science and Health. Champaign IL: Human Kinetics. ISBN: 0736063439. (see Human Kinetics website)

Pescatello, L.S., S.M. Roth (Co-editors). (2011) Exercise Genomics (in the Molecular and Translational Medicine series). Humana Press. 287 pages. ISBN: 9781607613541. (see Humana website)


Research Articles:
Search PubMed for recent publications

Recent, representative publications (* indicates student advisee):

  1. Roth, S.M.†, S. Walsh*, D. Liu*, E.J. Metter, L. Ferrucci, B.F. Hurley. The ACTN3 R577X nonsense allele is under-represented in elite-level strength athletes. European Journal of Human Genetics, 16: 391-394, 2008. (PMCID: PMC2668151)
  2. Charbonneau, D.E.*, E.D. Hanson, A.T. Ludlow*, M.J. Delmonico, B.F. Hurley, S.M. Roth†. ACE genotype and the muscle hypertrophic and strength responses to strength training. Medicine and Science in Sports and Exercise, 40: 677-683, 2008.
  3. Deeny, S.P., D. Poeppel, J.B. Zimmerman, S.M. Roth, J. Brandauer, S. Witkowski, J.W. Hearn, A.T. Ludlow*, J.L. Contreras-Vidal, J. Brandt, B.D. Hatfield†. Exercise, APOE, and working memory: MEG and behavioral evidence for benefit of exercise in epsilon4 carriers. Biological Psychology, 78: 179-187, 2008.
  4. Liu, D.*, E.J. Metter, L. Ferrucci, S.M. Roth†. TNF promoter polymorphisms associated with muscle phenotypes in humans. Journal of Applied Physiology, 105: 859-867, 2008. (PMCID: PMC2536817)
  5. Roth, S.M.†, S.M. Williams, L. Jiang, K.S. Menon, J.J. Jeka.  Susceptibility genes for gentamicin-induced vestibular dysfunction. Journal of Vestibular Research, 18: 59-68, 2008. (PMCID: PMC2581796)
  6. Roth, S.M. Functional genomics and the path to personalized medicine. Commentary article for Exercise and Sport Sciences Reviews, 36: 49-50, 2008.
  7. Roth, S.M. Viewpoint: Perspective on the future use of genomics in exercise prescription. Unsolicited commentary for Journal of Applied Physiology, 104: 1243-1245, 2008. [See associated invited commentaries on pages 1246-1253 in this same issue.]
  8. Ludlow, A.T.*, J.B. Zimmerman, S. Witkowski, J.W. Hearn, B.D. Hatfield, S.M. Roth†. Relationship between physical activity, telomere length, and telomerase activity. Medicine and Science in Sports and Exercise, 40: 1764-1771, 2008. (PMCID: PMC2581416)
  9. Walsh, S.*, D. Liu*, E.J. Metter, L. Ferrucci, S.M. Roth†. ACTN3 genotype is associated with muscle phenotypes in women across the adult age span. Journal of Applied Physiology, 105: 1486-1491, 2008. (PMCID: PMC2584847)
  10. Delmonico, M.J., J.M. Zmuda, B.C. Taylor, J.A. Cauley, T.B. Harris, T.M. Manini, A. Schwarz, R. Li, S.M. Roth, B.F. Hurley, D.C. Bauer, R.E. Ferrell, A.B. Newman†. Association of the ACTN3 genotype and physical functioning with age in older adults. Journal of Gerontology Medical Sciences, 63A, 1227-1234, 2008.
  11. Fenty-Stewart, N., J.Y. Park, S.M. Roth, J.M. Hagberg, S. Basu, R.E. Ferrell, M.D. Brown†. Independent and combined influence of AGTR1 variants and aerobic exercise on oxidative stress in hypertensives. Blood Pressure, 18: 204-212, 2009.
  12. Bray, M.S., J.M. Hagberg, L. Pérusse, Rankinen, T., S.M. Roth, B. Wolfarth, C. Bouchard†. The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Medicine and Science in Sports and Exercise, 41: 34-72, 2009.
  13. Faulkner, K.A., J.A. Cauley, S.M. Roth, C. Kammerer, K. Stone, T.A. Hillier, K.E. Ensrud, M. Hochberg, M.C. Nevitt, J.M. Zmuda†. Familial resemblance and shared latent familial variance in recurrent fall-risk in older women. Journal of Applied Physiology, 108: 1142-1147, 2010.
  14. Rankinen, T., S.M. Roth, M.S. Bray, R. Loos, L. Perusse, B. Wolfarth, J.M. Hagberg, C. Bouchard. Advances in exercise, fitness and performance genetics. Medicine and Science in Sports and Exercise, 42(5): 835-846, 2010.
  15. Hanson, E.D.*, A.T. Ludlow*, A.K. Sheaff, J. Park, S.M. Roth†. ACTN3 genotype does not influence muscle power. International Journal of Sports Medicine, 31: 834-838, 2010.
  16. Lima, R.M.*, T.K.M. Leite, R.W. Pereira, H.T. Rabelo, S.M. Roth, R.J. Oliveira. ACE and ACTN3 genotypes in older women: muscular phenotypes. International Journal of Sports Medicine, 32: 66-72, 2011.
  17. Windelinckx, A., G. De Mars, W. Huygens, M. Peeters, B. Vincent, C. Wijmenga, D. Lambrechts, C. Delecluse, S.M. Roth, E.J. Metter, L. Ferrucci, J. Aerssens, R. Vlietinck, G. Beunen, M. Thomis. Comprehensive fine mapping of chr12q12-14 and follow-up replication identify activin receptor 1B (ACVR1B) as a muscle strength gene. European Journal of Human Genetics, 19: 208-215, 2011.
  18. McKenzie, J.A., S. Witkowski, A.T. Ludlow*, S.M. Roth, J.M. Hagberg. AKT1 G205T genotype influences obesity-related metabolic phenotypes and their responses to aerobic exercise training in older Caucasians. Experimental Physiology, 96.3: 338-347, 2011.
  19. Ludlow. A.T, S.M. Roth. Physical activity and telomere biology: exploring the link with aging-related disease prevention. Journal of Aging Research, vol. 2011, Article ID 790378, 12 pg, 2011. doi:10.4061/2011/790378
  20. Hagberg, J.M., T. Rankinen, R.J.F. Loos, L. Perusse, S.M. Roth, B. Wolfarth, C. Bouchard. Advances in exercise, fitness, and perforfdmance genomics in 2010. Medicine and Science in Sports and Exercise, 43(5): 743-752, 2011